GENTISYL ALCOHOL INHIBITS PROLIFERATION AND INDUCES APOPTOSIS VIA MITOCHONDRIAL DYSFUNCTION AND REGULATION OF MAPK AND PI3K/AKT PATHWAYS IN EPITHELIAL OVARIAN CANCER CELLS

Ovarian cancer is one Grinders of the prevalent gynecological cancers occurring in women.In particular, the efficiency of standard therapeutic methods decreases when recurrence and chemoresistance ensue.To assist standard anti-cancer agents in the cure of ovarian cancer, development and application of new compounds such as small molecules or natura

Abstract In complicated urban environments, Global Navigation Satellite System (GNSS) signals are frequently affected by building reflection or refraction, resulting in Non-Line-of-Sight (NLOS) errors.In severe cases, NLOS errors can cause a ranging error of hundreds of meters, which has a substantial impact on the precision and dependability of GN

Summary: Herein, with the help of experimental and first-principles density functional theory (DFT)-based studies, we have shown that structural changes in the water coordination in electrolytes having high alkalinity can be a possible reason for the reduced catalytic activity of platinum (Pt) in high pH.Studies with polycrystalline Pt electrodes i

Pathological mutations in GBA, encoding lysosomal glucocerebrosidase (GCase), cause Gaucher disease (GD).GD is a multi-system disease with great phenotypic variation between individuals.It has been classified into type 1 with primarily peripheral involvement and types 2 and 3 with varying degrees of neurological involvement.GD is characterized by d